Important Information about PROTONIX
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Your talk with your doctor may be easier if you know what you want to ask. To help you get the most from your conversation, consider printing out these questions to take along with you.

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• • Could my symptoms be caused by erosive acid reflux disease?
• • Could erosions be developing in my esophagus?
• • What are my treatment options?
• • Is PROTONIX right for me?
• • What should I expect from treatment?
• • Are there any side effects I should be concerned about?
• • How long will it take before I see results?
• • How will I know if my treatment is working?

Important Product and Safety Information

Indications

PROTONIX is a prescription drug that is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), and relieve associated symptoms that may include frequent and persistent heartburn and stomach acid backup. Most patients heal within 8 weeks of treatment. Doctors may prescribe PROTONIX beyond 8 weeks to maintain healing or to prevent a recurrence of your symptoms. Controlled studies did not extend beyond 12 months.

Important Safety Information

In clinical trials, the most frequently reported side effects with PROTONIX Delayed-Release Tablets were headache, diarrhea, and gas. Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions are present. Patients who are allergic to any ingredient of PROTONIX should not take it.

Please see Important Prescribing Information.