Important Information about PROTONIX
Read more below.

If you take PROTONIX as directed and start feeling better, you're on the right track. But that doesn't mean you should stop taking your medication. Damage in the esophagus from erosive acid reflux disease may still need time to heal.

A good reason to stick with it.

What may happen if you stop treatment early or don't take PROTONIX as directed? The damage may remain unhealed and symptoms may return. So take PROTONIX for as long as your doctor recommends. Studies show PROTONIX can heal erosions caused by acid reflux disease in many people in just 8 weeks. Individual results may vary.

Help keep damage from making a comeback.

Did you know that even after the healing, acid reflux can return? It's true. After stopping your medication, stomach acid levels can rise again. And if acid reaches the esophagus, it can cause erosions to develop.

Studies have shown that some patients with healed erosions in their esophagus experience a return of symptoms once they stop taking a proton pump inhibitor such as PROTONIX. Doctors may prescribe PROTONIX beyond 8 weeks to help maintain healing and prevent symptoms from coming back.

To help you make the most of your PROTONIX treatment, you can also take advantage of the RENEW program, a free informational program that gives you facts about your condition and what you can do about it.

Important Product and Safety Information

Indications

PROTONIX is a prescription drug that is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), and relieve associated symptoms that may include frequent and persistent heartburn and stomach acid backup. Most patients heal within 8 weeks of treatment. Doctors may prescribe PROTONIX beyond 8 weeks to maintain healing or to prevent a recurrence of your symptoms. Controlled studies did not extend beyond 12 months.

Important Safety Information

In clinical trials, the most frequently reported side effects with PROTONIX Delayed-Release Tablets were headache, diarrhea, and gas. Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions are present. Patients who are allergic to any ingredient of PROTONIX should not take it.

Please see Important Prescribing Information.