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PROTONIX® (pantoprazole sodium) Tools and Resources

Tools and Resources

It’s important to take an active role in managing your erosive gastroesophageal reflux disease (erosive GERD) and to have open and honest conversations with your doctor. By downloading and printing the support tools and resources shown below, you may learn how to monitor your health conditions and stay on track with the treatment plan your doctor prescribes. If eligible, monthly brand-name savings may also be available to you!

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The PROTONIX Patient Journal
Write down the symptoms you experience every day, and keep track of your experience while taking brand-name PROTONIX. Talk to your doctor right away if your symptoms get worse. You can review results with your doctor during your next office visit to make sure PROTONIX is still an appropriate part of your treatment plan.
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The PROTONIX Savings Card*
Find out how your monthly co-pay may be as little as $4 and how you may save up to $70 per 30-day fill of brand-name PROTONIX. If you’re eligible for this savings offer, you can print a temporary card and start saving at the pharmacy today.
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The PROTONIX BRAND Savings Guide
Remember, the PROTONIX Savings Card only works with brand-name PROTONIX. Refer to these helpful tips when having conversations at your doctor’s office and at the pharmacy. They may help you get the brand-name product and savings you want!

*Terms and conditions apply.

Important Safety Information
  • Patients who are allergic to pantoprazole sodium or any of the other ingredients of PROTONIX or other proton pump inhibitors (PPIs) should not take PROTONIX.
  • Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions may be present. Talk with your doctor.
  • A very serious allergic reaction to this drug is rare. Get medical help right away if you notice any symptoms of a serious allergic reaction, including throat tightness, fever, rash, difficult breathing, weight loss, feeling tired, and weakness as this may be a serious allergic reaction.
  • Some people who take proton pump inhibitor (PPI) medicines, including PROTONIX, may develop a kidney problem called acute interstitial nephritis that can happen at any time during treatment with PROTONIX. Call your doctor if you have a decrease in the amount that you urinate or if you have blood in your urine.
  • PROTONIX may increase the risk of getting severe diarrhea due to an intestinal infection caused by Clostridium difficile. Call your doctor right away if you have diarrhea, cramps, and fever that does not go away. Patients should use the lowest dose and shortest duration of PPI appropriate to the condition being treated.
  • PPI therapy, like PROTONIX, may be associated with an increased risk of bone fractures of the hip, wrist or spine. The risk of fracture increases in patients who are taking multiple daily doses and are on PPI therapy for a year or longer.
  • Some people who take proton pump inhibitors (PPIs), including PROTONIX, develop certain types of lupus erythematosus or have worsening of the lupus they already have. Call your doctor right away if you have joint pain or rash on your cheeks or arms that gets worse in the sun.
  • PROTONIX reduces the amount of acid in your stomach. Stomach acid is needed to absorb vitamin B-12 properly. Talk with your doctor about the possibility of vitamin B-12 deficiency if you have been on PROTONIX for a long time (more than 3 years).
  • Low magnesium levels can happen in some patients who take proton pump inhibitors, like PROTONIX, for at least 3 months. Tell your doctor right away if you have any of these symptoms of low magnesium: seizures, dizziness, irregular heartbeat, muscle spasms or cramps.
  • The most frequently reported side effects for PROTONIX in adults were headache, diarrhea, nausea, abdominal pain, vomiting, gas, dizziness, and joint pain.
  • The most frequently reported side effects for PROTONIX in children 1 to 16 years of age were upper respiratory infections, headache, fever, diarrhea, vomiting, rash, and abdominal pain.
  • Before taking PROTONIX, tell your doctor about all of the medicines you take, especially: an antibiotic that contains ampicillin, atazanavir, iron salts, ketoconazole, nelfinavir, erlotinib, mycophenolate mofetil (MMF), or warfarin. If you are taking PROTONIX with warfarin, you may need to have certain laboratory tests monitored as potential serious risks may occur.
  • Use of PROTONIX along with high doses of methotrexate may increase blood levels of methotrexate, possibly leading to methotrexate toxicity.
  • PROTONIX is a prescription drug for the short-­term treatment in the healing and relief of symptoms of acid-­related damage to the esophagus. This condition is known as erosive esophagitis or erosive gastroesophageal reflux disease (GERD) and is caused by back up of stomach acid into the esophagus.
  • PROTONIX can be used for adults and children 5 years of age and older for treatment up to 8 weeks. Adults can receive an additional 8 weeks of treatment if needed. Safety of treatment beyond 8 weeks has not been established in children. PROTONIX can be used to maintain healing of erosive GERD in adults. Studies did not go beyond 12 months.
  • PROTONIX is used in adults for the long-term treatment of conditions where your stomach makes too much acid. This includes a rare condition called Zollinger-Ellison syndrome.

Please see full Prescribing Information, including Medication Guide.

Patients should always ask their doctors for medical advice about adverse events.

You may report an adverse event related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where health care professionals and consumers can report serious problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit MedWatch or call 1-800-FDA-1088.

© 2017 Pfizer Inc.All rights reserved.PP-PRX-USA-0130-01

Scroll for Important Safety Information and Indications

Important Safety Information
  • Patients who are allergic to pantoprazole sodium or any of the other ingredients of PROTONIX or other proton pump inhibitors (PPIs) should not take PROTONIX.
  • Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions may be present. Talk with your doctor.
  • A very serious allergic reaction to this drug is rare. Get medical help right away if you notice any symptoms of a serious allergic reaction, including throat tightness, fever, rash, difficult breathing, weight loss, feeling tired, and weakness as this may be a serious allergic reaction.
  • Some people who take proton pump inhibitor (PPI) medicines, including PROTONIX, may develop a kidney problem called acute interstitial nephritis that can happen at any time during treatment with PROTONIX. Call your doctor if you have a decrease in the amount that you urinate or if you have blood in your urine.
  • PROTONIX may increase the risk of getting severe diarrhea due to an intestinal infection caused by Clostridium difficile. Call your doctor right away if you have diarrhea, cramps, and fever that does not go away. Patients should use the lowest dose and shortest duration of PPI appropriate to the condition being treated.
  • PPI therapy, like PROTONIX, may be associated with an increased risk of bone fractures of the hip, wrist or spine. The risk of fracture increases in patients who are taking multiple daily doses and are on PPI therapy for a year or longer.
  • Some people who take proton pump inhibitors (PPIs), including PROTONIX, develop certain types of lupus erythematosus or have worsening of the lupus they already have. Call your doctor right away if you have joint pain or rash on your cheeks or arms that gets worse in the sun.
  • PROTONIX reduces the amount of acid in your stomach. Stomach acid is needed to absorb vitamin B-12 properly. Talk with your doctor about the possibility of vitamin B-12 deficiency if you have been on PROTONIX for a long time (more than 3 years).
  • Low magnesium levels can happen in some patients who take proton pump inhibitors, like PROTONIX, for at least 3 months. Tell your doctor right away if you have any of these symptoms of low magnesium: seizures, dizziness, irregular heartbeat, muscle spasms or cramps.
  • The most frequently reported side effects for PROTONIX in adults were headache, diarrhea, nausea, abdominal pain, vomiting, gas, dizziness, and joint pain.
  • The most frequently reported side effects for PROTONIX in children 1 to 16 years of age were upper respiratory infections, headache, fever, diarrhea, vomiting, rash, and abdominal pain.
  • Before taking PROTONIX, tell your doctor about all of the medicines you take, especially: an antibiotic that contains ampicillin, atazanavir, iron salts, ketoconazole, nelfinavir, erlotinib, mycophenolate mofetil (MMF), or warfarin. If you are taking PROTONIX with warfarin, you may need to have certain laboratory tests monitored as potential serious risks may occur.
  • Use of PROTONIX along with high doses of methotrexate may increase blood levels of methotrexate, possibly leading to methotrexate toxicity.
INDICATIONS
  • PROTONIX is a prescription drug for the short-term treatment in the healing and relief of symptoms of acid-related damage to the esophagus. This condition is known as erosive esophagitis or erosive gastroesophageal reflux disease (GERD) and is caused by back up of stomach acid into the esophagus.
  • PROTONIX can be used for adults and children 5 years of age and older for treatment up to 8 weeks. Adults can receive an additional 8 weeks of treatment if needed. Safety of treatment beyond 8 weeks has not been established in children. PROTONIX can be used to maintain healing of erosive GERD in adults. Studies did not go beyond 12 months.
  • PROTONIX is used in adults for the long-term treatment of conditions where your stomach makes too much acid. This includes a rare condition called Zollinger-Ellison syndrome.

Please see full Prescribing Information, including Medication Guide.


Patients should always ask their doctors for medical advice about adverse events.

You may report an adverse event related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where health care professionals and consumers can report serious problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit MedWatch or call 1-800-FDA-1088.